Methadone Hydrochloride Oral Solution Supplier

Oral Dosage :

  • Adults : Medical withdrawal from methadone should be done in decrements as tolerated by the patient on a daily basis or at 2-day intervals. The dose should be sufficient to keep withdrawal symptoms at a tolerable level. Many hospitalized patients may tolerate a daily dosage reduction of 20%. In ambulatory patients, a somewhat slower schedule may be required. Patients should be allowed to discontinue withdrawal at anytime, for any reason, without feelings of guilt. They should then be placed into a methadone maintenance program at an appropriate dose. Any decrease in methadone dosage could precipitate a relapse to drug use. Methadone use is preferable to the use of illegal street drugs.
  • Pregnant women : Medical withdrawal of methadone maintenance is generally not recommended during pregnancy. If required, methadone withdrawal is done in decrements of 2 to 2.5 mg every 7 to 10 days. This should be done in conjunction with an obstetrician who can monitor the effects on the fetus.
  • Adults, including pregnant women : 20 to 30 mg PO initially unless low opioid tolerance is expected; use a lower initial dose for these patients. Additional doses of 5 to 10 mg of methadone PO may be given 2 to 4 hours after the initial dose if withdrawal symptoms have not been suppressed or if symptoms reappear. The total daily oral dose on Day 1 should not ordinarily exceed 40 mg. Dosage adjustments on subsequent days should be based on withdrawal symptom control at the time of expected peak methadone activity (2 to 4 hours after dosing). Due to the extended half-life of methadone, it may take up to 5 days to achieve a steady-state dose that controls symptoms of opiate withdrawal. Prior to achieving steady state, adequate total daily doses may not hold patients for a full 24 hours. Deaths have occurred in early treatment due to the cumulative effects of methadone. The stabilizing dose is continued for 2 to 3 days


Storage :

  • Generic : Store between 68 to 77 degrees F, excursions permitted 59 to 86 degrees F
  • Dolophine : Protect from light, Store at controlled room temperature (between 68 and 77 degrees F), Store in carton until contents are used
  • Methadose : Store at 77 degrees F; excursions permitted to 59-86 degrees F



Pack size 500ml
Form Liquid
Best Before 24 months from Manufacture date
Oral dosage As per doctors prescription
STORAGE Store between 68 to 77 degrees F, excursions permitted 59 to 86 degrees F , Protect from light
Grade Medicine Grade

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